Using skills in nucleic acids chemistry, cyclodextrin chemistry and synthetic chemistry, we are developing new materials and technologies to contribute in life and material sciences.

Our research focuses on interfacial phenomena and self-assembling related to emulsification, solubilization and dispersion, which can be the basis for cosmetic formulations. We often utilize various physicochemical methods such as rheology, spectrometry, calorimetry, etc. to evidence the mechanisms and functions of these phenomena. In particular, we have been challenging microgravity experiments for several years and exploring new findings in non-equilibrium colloidal dispersion systems such as emulsion. Besides such physicochemical topics, we also undertake dermatological researches on transdermal absorption and skin effectiveness of cosmetics (or ingredient).

In recent years, much progress has been made in research on human resident microbiota. The entire picture of resident microbiota is being clarified not only with respect to the types and proportions of bacteria that constitute the microbiota but also the crosstalk between bacteria. As resident microbiota is deeply involved in human health, disruption of their balance and loss of diversity (dysbiosis) cause poor health and disease. We aim to improve physical and skin conditions based on regulation of the resident microbiota via food function.

By analyzing the DNA of various organisms, we can decipher the history of evolution (or selective breeding) of each organism. This also allows us to understand the diversity of these organisms. In particular, we are analyzing the diversity of crop varieties at the DNA level and developing DNA markers in order to obtain new knowledge that can contribute to selective crop breeding. We are also working on developing experimental programs that contribute to the education of molecular biology content.

We conduct research on auxin, which is a plant hormone that plays an important role in every stage of plant growth. Our laboratory is currently conducting research using inhibitors, etc., with the aim of clarifying the role of auxin in Arabidopsis root morphogenesis.

Bioactive natural products chemistry; discovery and identification, chemical synthesis, and biosynthesis and function.

Development of artificial enzymes based on coordination compounds and solid supports. (1) Design and development of metallocomplex catalysts (homogeneous catalysts & heterogeneous immobilized catalysts) applicable to green oxidation reactions. (2) Investigation on the reaction mechanism of active oxygen complexes with transition metals.

Development of new synthetic methods by generating organometallic catalyst and reagents and their application to synthesis of biologically active compounds and polymer chemistry. Development of new synthetic reactions using low-valent titanium reagent, metal catalysts or organic catalysts. Design and synthesis of vitamin D derivatives and evaluation of their biological activity. Development of new polymerization methods based on metal catalyst or reagent and its application to functional polymer materials. Design and synthesis of auxin derivatives and evaluation of their biological activity.